As soon as you are at the $145k income level you should be able to purchase a home in the price range you are considering, with likely a payment on $270k at around $2,100 as well.
Few questions though.
#1, is the new employment/income in 8/08 going to be salary? If so, you only need to be working at the new salary for a day in order for it to qualify, but since it's a new employer, lenders will likely want you to get at least 1 paycheck showing that amount.
#2, where are you planning on purchasing? This will determine what you should expect in terms of homeowners insurance, property taxes, and possibly required down payment.
#3, do you have a down payment, or any reserves/assets (such as savings, checking, 401k, IRA, stocks, etc.)?
#4, will any of the $2,200/mo in debt have 10 payments or less by the time you are ready to apply?
#2, & #3 would have some bearing on what your monthly payment would be.
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