A citi Double Cash and a Custom Cash could be a good combo perhaps. The DC for uncapped 2% and the CC for 5% (capped) on the travel category (or other you choose). They earn ThankYou points which can be redeemed through the Citi Travel Portal. Also having the Prestige, Premier, or AT&T Access More cards can sometimes increase the transfer rate. I have no experience with this, I take the Cash Back, lol, so sorry if this is not a good idea. Just thought I'd through it out there. 
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Amex gold and pair that w/ rakuten for shopping and dining program.
That's your best bet to rack up MR points really, really quickly on top of the SUB.
I like Navy Flagship and Amex Gold for daily use.
I think it depends on how much travel and also how you travel (rail, air, bus, boat, hotel, air B&B, etc) along with how this compares to your every day spending. I.e. what percent is travel compared to your overall spending? Also, by how you asked the question, I assume you are looking for a single card and aren't looking to try and break things up over multiple cards?
There are a number of cards you could potentially choose from depending on how you answered the above questions. I prefer to split things by spending category and would suggest the following:
- If you spend a lot of nights at hotels, grab whatever loyalty card makes sense for you. I have the Marriott Bonvoy Card from AMX that is $95 a year but offers a 35K award which we easily use. This is the only AF card I have.
- For a general hotel and air travel card, it's hard to beat the GreenState Federal Credit Union Card. This is pseudo geo restricted but it's easy enough to join one of the aligned associations to become a member. Their World Mastercard offers 5X points on purchased (5% cash back via a statement credit) and has no AF
- If you travel outside of air and hotel, the PenFed Pathfinder card has NO AF but does have some account requirements like parking $500. This card has 4X points on nearly every travel category but on redemption is closer to 3.4% due to devaluation of cash equivalent redemptions. Another nice thing about this card is the Global Entry and TSA reimbursement. They also have mobile phone coverage if your monthly plan is purchased on the card
- If you travel by air and infrequently use lounges, the US Bank Altitude Connect offers 4 lounge visits a year and has no AF (waived for year 1 and will permanently be gone Sept 1 this year). This card also offers a TSA/Global Entry reimbursement, so if you and another family member want TSA/Global Entry, between the PenFed and this Card you would be covered
- For regular every day spending, since AOD 3% CB is no longer available, your best bet is the 2.5% CB from Alliant Credit Union (up to $10K monthly) and also has no AF. I don't have personal experience with this card, but 2.5% cards are more rare these days
I generally don't recommend cards with AF unless you are 100% certain you will get your money back without a forced spend. For example, some Amex cards like the Platinum Card offer a $200 Uber Eats credit which I normally would never use. If that's part of your yearly spend, great, otherwise it's a forced spend to get your money back on the AF. That combined with travel cards that can offer 5% with no annual fee make cards like the Amex more challenging ROI. That said, there are people on this forum that travel extensively and, for them, something like the Amex Platinum makes sense. It really comes down to the first set of questions I posed above.
Starting Score: 800Lol, enough w/ CB suggestions......It's a travel card thread.
Chase CSR paired w/ Freedom Unlimited also is a great combo. CSR 10x car rentals and 10x booking on their travel portal makes this card a great independent hotel card, in addition Chase has a shopping portal to make up for non-cat spend.
Also, their transfer partners are very good, especially having Hyatt as one, plus 1.50x floor for travel redemptions. As everyone knows most of these cards come with AFs because there is a reason for that, the ability to get greater than 1:1 and have a flex point ecosystem.
One might argue NFCU's Flagship Rewards could be considered the best all around card for both Travel and Everyday.
